Capping And Lamination Of Tablets

First lamination is caused by air being trapped in the tablet especially among the granules or particles. Lamination is separation that occurs at any other part of the tablet except the top or bottom. Capping happens when the upper or lower part of a tablet separates horizontally photo as the press ejects the tablet.

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Ejection issues could lead to lamination.

Capping and lamination of tablets.

If a fracture occurs in the lower part of the tablet it is referred to as lamination and is discussed below. Lamination is also caused by the presence of a large amount of fines in the granulations. Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process. The term tablet capping is used when either the upper or lower part of the tablet separates horizontally either partially away from the main body or completely to form a cap when ejected from the press or during the handling process.

As the air is released when the upper punch die tip is raised capping only occurs at the top of the tablet. This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate. Capping and lamination are common defects that occur during tablet manufacturing. Although the method is widely used there are still significant challenges with achieving a high quality compact.

Compressing the tablet too thin the only common factor between capping and lamination usually occurs at precompression causing the tablets to compress in layers and the layers will separate as tablets cool or the bottom layer will separate from top during ejection.

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